Understanding GPD1: A Potential Drug Target (G2819)
Understanding GPD1: A Potential Drug Target
GPD1 (G protein-coupled receptor 1) is a protein that is expressed in many different tissues and cells in the body. It is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. GPD1 is one of the most well-studied G protein-coupled receptors, and is known for its role in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and cellular signaling.
GPD1 is an isoform and there are several different genotypes. GPD1 genotypes include wild type (WT), deleted modified gene (DM), and mutant genotypes. The protein encoded by the WT genotype contains 514 amino acids, while the protein encoded by the DM genotype contains only 489 amino acids. The protein encoded by the Mutant genotype contains 522 amino acids, which is 3 more amino acids than the WT genotype.
GPD1 is a membrane protein found on the inside of the cell membrane. It has five transmembrane alpha helices, one on the inside of the cell membrane and the other four on the outside. The 伪-helix of GPD1 consists of 35 amino acids and accounts for 36.5% of the total protein.
GPD1 is a ligand-binding protein that can bind ligand molecules, such as drugs, chemicals, or other signaling molecules. The ligand binding site of GPD1 is located on the outside of the cell membrane. Through ligand binding, GPD1 can trigger a series of signal transduction pathways to regulate cellular physiological processes.
Because GPD1 plays an important role in a variety of physiological processes, it is considered a potential drug target. Researchers are exploring the role of GPD1 in treating a variety of diseases, including neurological diseases, endocrine diseases, and cardiovascular diseases.
As a drug target, GPD1 has high research value. First, by studying the pharmacological properties of GPD1, we can better understand the mechanism of action of drugs and provide guidance for the development of new drugs. Secondly, studying the role of GPD1 in disease can provide new treatment methods and drug targets for medicine. Finally, studying the structure and function of GPD1 can provide new ideas and methods for drug design.
GPD1 is an important drug target with broad application prospects. Further research on the structure and function of GPD1 can provide guidance for the development of new drugs and provide new treatment methods and drug targets for medicine.
Protein Name: Glycerol-3-phosphate Dehydrogenase 1
Functions: Has glycerol-3-phosphate dehydrogenase activity
The "GPD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPD1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A
