GPHN: A unique protein involved in neurotransmission (G10243)
GPHN: A unique protein involved in neurotransmission
GPHN, or Gephyrin transcript variant 2, is a protein that is expressed in the brain and nervous system. It is a member of the Gephyrin gene family, which is known for the production of receptor proteins that play a critical role in the neurotransmitter signaling system. GPHN is a unique protein, as it is only expressed in the brain and nervous system, and it is not found in any other tissues or cells in the body.
The GPHN protein is known for its role in the neurotransmitter signaling system, specifically in the regulation of neurotransmitter release. It is a key regulator of the neurotransmitter release, and is involved in the production and release of a variety of neurotransmitters, including GABA, serotonin, and dopamine. GPHN is also involved in the regulation of neurotransmitter uptake and storage, as well as the modulation of neurotransmitter release by other molecules.
GPHN is a transmembrane protein, which means that it spans the cell membrane and is located in the brain and nervous system. It is characterized by a long extracellular domain that is involved in its interactions with other molecules, as well as a short intracellular domain that is involved in its localization and stability. The intracellular domain of GPHN contains a unique feature, known as a N-terminal transmembrane domain, which is involved in the regulation of GPHN's stability and localization.
GPHN is a unique protein that is expressed in only the brain and nervous system. It is not found in any other tissues or cells in the body, and it is not known to have any function outside of these cells. Despite its unique expression, GPHN is of great interest to researchers because of its role in the neurotransmitter signaling system. The study of GPHN and its function in the brain and nervous system may lead to new insights into the mechanisms of neurotransmission and the development of new treatments for a variety of neurological and psychiatric disorders.
In conclusion, GPHN is a protein that is expressed in the brain and nervous system that is involved in the regulation of neurotransmitter release. It is a unique protein that is not found in any other tissues or cells in the body, and its role in the neurotransmission system is of great interest to researchers. Further studies of GPHN and its function in the brain and nervous system may lead to new insights into the mechanisms of neurotransmission and the development of new treatments for a variety of neurological and psychiatric disorders.
Protein Name: Gephyrin
Functions: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed:25025157, PubMed:26613940)
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More Common Targets
GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A | GPR89B | GPRACR | GPRASP1 | GPRASP2 | GPRASP3 | GPRC5A
