Target Name: GPCPD1
NCBI ID: G56261
Review Report on GPCPD1 Target / Biomarker Content of Review Report on GPCPD1 Target / Biomarker
GPCPD1
Other Name(s): glycerophosphocholine phosphodiesterase GDE1 homolog | EDI3 | preimplantation protein 4 | endometrial differential 3 | Glycerophosphodiester phosphodiesterase 5 | Glycerophosphocholine phosphodiesterase GPCPD1 | Putative glycerophosphocholine phosphodiesterase GPCPD1 | putative glycerophosphocholine phosphodiesterase GPCPD1 | Glycerophosphocholine phosphodiesterase 1 | KIAA1434 | Putative glycerophosphodiester phosphodiesterase 5 | GPCP1_HUMAN | glycerophosphodiester phosphodiesterase 5 | GDPD6 | Preimplantation protein 4 | RP5-1022P6.2 | PREI4 | putative glycerophosphodiester phosphodiesterase 5 | GDE5 | NARC16 | glycerophosphocholine phosphodiesterase 1

GPCPD1: Key Enzyme in Cholesterol Homeostasis and TGF-β Signaling

GPCPD1 (Glycerophosphocholine Phosphodiesterase GDE1 Homolog) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and lungs. It is a member of the GPCR (G-protein-coupled receptor) family, which is a well-established transmembrane protein that plays a critical role in cellular signaling. GPCPD1 is involved in the intracellular signaling pathway known as the Cholesterol Homeostasis, which is responsible for maintaining the structural and functional integrity of cellular organelles.

GPCPD1 functions as a key enzyme in the degradation of a type of cholesterol called low-density lipoprotein (LDL) cholesterol. LDL cholesterol is a major risk factor for the development of cardiovascular disease, as it can contribute to the formation of plaque in the arteries. By breaking down LDL cholesterol, GPCPD1 helps to maintain a healthy balance of cholesterol in the bloodstream.

In addition to its role in cholesterol homeostasis, GPCPD1 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the signaling pathway known as the TGF-β (Transforming Growth Factor-β) pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and maintenance of tissues.

GPCPD1 is also involved in the regulation of the Wnt signaling pathway, which is involved in the development and maintenance of tissues and organs. This pathway is a key factor in the regulation of stem cell proliferation and the formation of tissues during development.

GPCPD1 is a potential drug target for the treatment of various diseases, including cardiovascular disease and cancer. For example, GPCPD1 has been shown to be highly expressed in the brains of individuals with Alzheimer's disease, a progressive neurodegenerative disorder. Studies have also shown that individuals with certain genetic variations in the GPCPD1 gene are at increased risk for the development of cardiovascular disease.

In addition to its potential clinical applications, GPCPD1 is also an attractive biomarker for the diagnosis and monitoring of various diseases. For example, the levels of GPCPD1 have been shown to be elevated in individuals with certain types of cancer, and may be a useful biomarker for the detection and prognosis of these diseases.

Overall, GPCPD1 is a protein that plays a critical role in the regulation of cellular signaling pathways and is involved in the intracellular signaling pathway known as the Cholesterol Homeostasis. It is a potential drug target for the treatment of various diseases, including cardiovascular disease and cancer, and is also an attractive biomarker for the diagnosis and monitoring of these diseases. Further research is needed to fully understand the role of GPCPD1 in cellular signaling and its potential as a drug and biomarker.

Protein Name: Glycerophosphocholine Phosphodiesterase 1

Functions: May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity

The "GPCPD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPCPD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88