WDR20: Key Regulator of Development and Maintenance (G91833)
WDR20: Key Regulator of Development and Maintenance
WDR20 (Wnt-repeat-containing protein 20) is a protein that is expressed in various tissues throughout the body, including the nervous system, endocrine system, and reproductive system. It is a key regulator of development and maintenance, and is involved in a wide range of physiological processes.
One of the unique features of WDR20 is its ability to repeat a wnt gene, which is a developmental transcription factor that is important for the formation of neural tube and the development of the nervous system. The repeated wnt gene is thought to contribute to the protein's ability to promote the formation of new neurons and the formation of neural connections.
WDR20 is also involved in the regulation of stem cells and their proliferation. It has been shown to play a role in the self-renewal of stem cells and has been shown to be important for the development and maintenance of neural stem cells.
In addition to its role in stem cells, WDR20 is also involved in the regulation of cell survival and death. It has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die naturally in the body.
WDR20 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cells, including T cells and macrophages.
In conclusion, WDR20 is a protein that is involved in a wide range of physiological processes, including the regulation of development and maintenance, the regulation of stem cells and their proliferation, the regulation of cell apoptosis, and the regulation of inflammation. As a result , it is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of WDR20 in these processes and to develop effective treatments.
Protein Name: WD Repeat Domain 20
Functions: Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336)
The "WDR20 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR20 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1 | WEE1 | WEE2 | WEE2-AS1 | WFDC1 | WFDC10A | WFDC10B | WFDC11 | WFDC12 | WFDC13 | WFDC2 | WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3
