Target Name: PLEKHG4B
NCBI ID: G153478
Review Report on PLEKHG4B Target / Biomarker Content of Review Report on PLEKHG4B Target / Biomarker
PLEKHG4B
Other Name(s): pleckstrin homology and RhoGEF domain containing G4B | PLEKHG4B variant X7 | KIAA1909 | Pleckstrin homology and RhoGEF domain containing G4B | Pleckstrin homology domain-containing family G member 4B (isoform X5) | PKH4B_HUMAN | Pleckstrin homology and RhoGEF domain containing G4B, transcript variant X7 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | pleckstrin homology domain-containing family G member 4B | PH domain-containing family G member 4B | Pleckstrin homology domain-containing family G member 4B

PLEKHG4B: Key Regulator of RhoA GTPase and G4 Family Protein

Pleckstrin homology (PH) and RhoGEF domain containing G4B, also known as PLEKHG4B, is a protein that plays a crucial role in various cellular processes. It is a member of the G4 family of proteins, which are known for their role in intracellular signaling. PLEKHG4B is widely expressed in various tissues and is involved in various cellular processes, including cell signaling, cell division, and tissue repair.

One of the key functions of PLEKHG4B is its role in intracellular signaling. It is a key regulator of the RhoA GTPase, which is involved in cell signaling and cell division. PLEKHG4B is part of a subfamily of G4 proteins that are known as the RhoA GTPase-associated protein (RhoA-associated protein) family. This subfamily includes proteins that are involved in intracellular signaling, including the myosin light chain kinase (MLCK), MLCK-associated protein (MLCK-AP), and PLEKHG1.

PLEKHG4B is a 21-kDa protein that is composed of 198 amino acid residues. It has a unique structure that includes a catalytic domain, a transmembrane region, and an N-terminus. The catalytic domain is the region of the protein that is involved in catalyzing various chemical reactions, such as the GTPase activity of PLEKHG4B. The transmembrane region is the region that spans the membrane of the cell and is involved in the regulation of the activity of PLEKHG4B. The N-terminus is the region of the protein that interacts with other proteins and is involved in the regulation of PLEKHG4B's activity.

PLEKHG4B is involved in various cellular processes, including cell signaling, cell division, and tissue repair. One of its key functions is its role in cell signaling. It is a key regulator of the RhoA GTPase, which is involved in the regulation of cell signaling and cell division. PLEKHG4B is part of a subfamily of G4 proteins that are known as the RhoA GTPase-associated protein (RhoA-associated protein) family. This subfamily includes proteins that are involved in intracellular signaling, including the myosin light chain kinase (MLCK), MLCK-associated protein (MLCK-AP), and PLEKHG1.

Pleckstrin homology (PH) is a structural protein that is composed of multiple domains, including a catalytic domain, a transmembrane region, and an N-terminus. It is a key regulator of the RhoA GTPase, which is involved in the regulation of cell signaling and cell division. PLEKHG4B is part of a subfamily of G4 proteins that are known as the RhoA GTPase-associated protein (RhoA-associated protein) family. This subfamily includes proteins that are involved in intracellular signaling, including the myosin light chain kinase (MLCK), MLCK-associated protein (MLCK-AP), and PLEKHG1.

Pleckstrin homology (PH) is a structural protein that is composed of multiple domains, including a catalytic domain, a transmembrane region, and an N-terminus. It is a key regulator of the RhoA GTPase, which is involved in the regulation of cell signaling and cell division. PLEKHG4B is part of a subfamily of G4 proteins that are known as the RhoA GTPase-associated protein (RhoA-associated protein) family. This subfamily includes proteins that are involved in intracellular signaling, including the myosin light chain kinase (MLCK), MLCK-associated protein (MLCK-AP), and PLEKHG1.

Pleckstrin homology (PH) is a protein that plays a crucial role in various cellular processes. It is a member of the G4 family of proteins, which are known for their role in intracellular signaling. PLEKHG4B is widely expressed in various tissues

Protein Name: Pleckstrin Homology And RhoGEF Domain Containing G4B

The "PLEKHG4B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLEKHG4B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3