Target Name: WDR11
NCBI ID: G55717
Review Report on WDR11 Target / Biomarker Content of Review Report on WDR11 Target / Biomarker
WDR11
Other Name(s): WD40 repeat domain 11 protein | DR11 | HH14 | WD repeat domain 11 | WDR15 | WD repeat-containing protein 15 | Bromodomain and WD repeat domain containing 2 | KIAA1351 | BRWD2 | DKFZp434L1715 | SRI1 | WDR11_HUMAN | bromodomain and WD repeat-containing protein 2 | WD repeat domain 15 | FLJ42531 | sensitization to ricin complex subunit 1 | WD repeat-containing protein 11 | Bromodomain and WD repeat-containing protein 2

Understanding WDR11: Potential Drug Target Or Biomarker

WDR11 (WD40 repeat domain 11 protein), also known as WDR11L1, is a protein that is expressed in various tissues and cells in the human body. It is a member of the WD40 gene family, which encodes a diverse set of non-coding RNAs that have been implicated in various cellular processes. One of the functions of these WD40 proteins is to interact with other proteins, including WDR11L2, a protein that is also known as WDR11.

In recent years, researchers have become increasingly interested in the study of WDR11 and its potential as a drug target or biomarker. This is because the WD40 gene family has been shown to be involved in a wide range of cellular processes, including cell adhesion, migration, and signaling. As such, these proteins may be useful for the development of new treatments for a variety of diseases.

One of the reasons for the interest in WDR11 is its potential as a drug target. The WD40 gene family has been shown to be involved in various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and progression of many diseases, including cancer.

Research has also suggested that WDR11 may be involved in the regulation of cell adhesion and migration. This is important because these processes are involved in the development of new tissues and organs, as well as in the regulation of tissues during development and development. As such, WDR11 may be a useful target for drugs that are aimed at preventing or treating the formation of new tissues or organs.

Another potential application of WDR11 is its role as a biomarker. This is because the WD40 gene family has been shown to be involved in the regulation of various cellular processes, including cell signaling and DNA replication. As such, the expression of these genes may be a useful indicator of the health and function of certain tissues or organs.

In addition to its potential as a drug target or biomarker, WDR11 is also of interest because of its expression pattern in various tissues and cells. Studies have shown that WDR11 is expressed in a variety of tissues and cells in the human body, including the brain, spinal cord, heart, and blood vessels. This suggests that it may be a useful biomarker for tracking the effects of drugs on these tissues and cells.

Overall, WDR11 is a protein that has the potential to be a drug target or biomarker, due to its involvement in various cellular processes and its expression pattern in various tissues and cells. Further research is needed to fully understand the role of this protein in the development and progression of diseases.

Protein Name: WD Repeat Domain 11

Functions: Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865)

The "WDR11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WDR11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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