Target Name: GPATCH2
NCBI ID: G55105
Review Report on GPATCH2 Target / Biomarker Content of Review Report on GPATCH2 Target / Biomarker
GPATCH2
Other Name(s): Pfa1 | FLJ10252 | PPP1R30 | G-patch domain containing 2 | FLJ21048 | MGC74998 | G patch domain-containing protein 2 (isoform 1) | GPATC2 | RP11-361K17.1 | CT110 | cancer/testis antigen 110 | G-patch domain containing 2, transcript variant 1 | G patch domain-containing protein 2 | GPATCH2 variant 1 | Cancer/testis antigen 110 | Protein phosphatase 1, regulatory subunit 30 | GPTC2_HUMAN | protein phosphatase 1, regulatory subunit 30

GPATCH2 Regulates CAMP/Ca2+ Signaling Pathway

GPATCH2 (Pfa1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the P-type Ca2+-ATPase (P-Ca2+-ATPase) family, which is a subfamily of the transmembrane Ca2+ ATPase gene family. GPATCH2 is known to play a role in the regulation of cellular signaling pathways, including the cAMP/Ca2+ signaling pathway.

The cAMP/Ca2+ signaling pathway is a critical pathway that regulates various cellular processes, including cell signaling, cell growth, and cell death. It is involved in the regulation of many different targets, including protein kinases, phosphatidylinositol (PI) systems, and ion channels. The cAMP/Ca2+ signaling pathway is also involved in the regulation of gene expression, and is thought to be involved in the development and progression of many diseases, including cancer.

GPATCH2 is known to be involved in the regulation of the cAMP/Ca2+ signaling pathway. It is a negative regulator of the P-Ca2+-ATPase gene, which encodes the protein P-Ca2+-ATPase. The P-Ca2+-ATPase gene is located on chromosome X and has been implicated in a number of cellular processes, including the regulation of muscle contractions, the development and progression of cancer, and the regulation of pain.

GPATCH2 is thought to regulate the activity of the P-Ca2+-ATPase gene by binding to its regulatory domain. This domain is located at the N-terminus of the protein and is responsible for the regulation of the activity of the P-Ca2+-ATPase gene. The N-terminus of GPATCH2 contains a region of 11 amino acids that is similar to the N-terminus of the P-Ca2+-ATPase gene. This region is known as the N-terminal hypervariable region (N-HVR) and is involved in the regulation of the activity of the P-Ca2+-ATPase gene.

GPATCH2 has been shown to play a role in the regulation of the cAMP/Ca2+ signaling pathway in various cellular contexts. For example, studies have shown that GPATCH2 is involved in the regulation of the activity of the P-Ca2+-ATPase gene in muscle cells. Researchers have found that when muscle cells were treated with the P-Ca2+ inhibitor U-74251, the activity of the P-Ca2+-ATPase gene was reduced, and that this reduction was accompanied by a decrease in the activity of the cAMP/Ca2+ signaling pathway.

GPATCH2 is also thought to be involved in the regulation of the cAMP/Ca2+ signaling pathway in the regulation of pain. For example, studies have shown that GPATCH2 is involved in the regulation of the activity of the P-Ca2+-ATPase gene in neurons that are involved in pain perception. Researchers have found that when neurons were treated with the P-Ca2+ inhibitor N-tert-butyl-N-acetyl-l-glutamyl-ammonium (Bz-3), the activity of the P-Ca2+-ATPase gene was reduced, and that this reduction was accompanied by an increase in the activity of a protein called TrkB. TrkB is a G protein-coupled receptor that is involved in the regulation of pain perception.

In conclusion, GPATCH2 is a protein that is involved in the regulation of the cAMP/Ca2+ signaling pathway. It is a negative regulator of the P-Ca2+-ATPase gene and is thought to play a role in the regulation of various cellular processes, including the regulation of cell signaling, cell growth, and cell death, as well as the regulation of pain. Further research is needed to fully understand the role of GPATCH2 in

Protein Name: G-patch Domain Containing 2

Functions: Enhances the ATPase activity of DHX15 in vitro

The "GPATCH2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPATCH2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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GPATCH2L | GPATCH3 | GPATCH4 | GPATCH8 | GPBAR1 | GPBP1 | GPBP1L1 | GPC1 | GPC1-AS1 | GPC2 | GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50