RNA-associated Nucleases: Targets for Cancer Treatment (G122651)
RNA-associated Nucleases: Targets for Cancer Treatment
RNA-associated Nucleases (RANs) are a family of enzymes that are involved in the processing of RNA. These enzymes are found in all living organisms and are involved in a wide range of cellular processes, including DNA replication, gene expression, and RNA degradation . One of the RANs that has garnered a lot of interest in recent years is RNASE11 (RAJ1), which is a member of the RNA-associated Nucleases family.
RNA-associated Nucleases (RANs) are a family of enzymes that are involved in the processing of RNA. These enzymes are found in all living organisms and are involved in a wide range of cellular processes, including DNA replication, gene expression, and RNA degradation . One of the RANs that has garnered a lot of interest in recent years is RNASE11 (RAJ1), which is a member of the RNA-associated Nucleases family.
RNA-associated Nucleases (RANs) are a family of enzymes that are involved in the processing of RNA. These enzymes are found in all living organisms and are involved in a wide range of cellular processes, including DNA replication, gene expression, and RNA degradation . One of the RANs that has garnered a lot of interest in recent years is RNASE11 (RAJ1), which is a member of the RNA-associated Nucleases family.
RNASE11 is an enzyme that is involved in the processing of RNA. It is a 23 kDa protein that is composed of two subunits that are located on opposite sides of a central alpha-helices. The subunits have a characteristic Rossmann-fold, which is a type of hydrogen bonding that allows them to bind to specific DNA sequences.
RNA-associated Nucleases (RANs) are a family of enzymes that are involved in the processing of RNA. These enzymes are found in all living organisms and are involved in a wide range of cellular processes, including DNA replication, gene expression, and RNA degradation . One of the RANs that has garnered a lot of interest in recent years is RNASE11 (RAJ1), which is a member of the RNA-associated Nucleases family.
The function of RNASE11 is to remove the phosphate groups from specific DNA sequences in RNA. This process is called RNA editing and is essential for the production of functional RNA molecules. RNASE11 is also involved in the processing of RNA in the ribosome, which is the machine that synthesizes proteins from RNA.
RNA-associated Nucleases (RANs) are a family of enzymes that are involved in the processing of RNA. These enzymes are found in all living organisms and are involved in a wide range of cellular processes, including DNA replication, gene expression, and RNA degradation . One of the RANs that has garnered a lot of interest in recent years is RNASE11 (RAJ1), which is a member of the RNA-associated Nucleases family.
RNA editing is a process that involves the removal of phosphate groups from specific DNA sequences in RNA. This process is essential for the production of functional RNA molecules. RNASE11 is also involved in the processing of RNA in the ribosome, which is the machine that synthesizes proteins from RNA.
The role of RNASE11 in the processing of RNA is multifaceted and is still not well understood. However, studies have shown that RNASE11 plays a critical role in the regulation of gene expression. It is known to interact with specific DNA sequences and to modulate the activity of other enzymes involved in gene expression, such as RNA polymerase II.
In addition to its role in gene expression, RNase11 is also involved in the processing of RNA in the ribosome. This process is critical for the production of proteins from RNA and is a target of many drugs that are used to treat various diseases, including cancer , HIV, and genetic disorders.
The use of RNA-associated Nucleases (RANs) as drug targets is a promising strategy for the development of new treatments for various diseases. By targeting
Protein Name: Ribonuclease A Family Member 11 (inactive)
The "RNASE11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RNASE11 comprehensively, including but not limited to:
• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
RNASE11-AS1 | RNASE12 | RNASE13 | RNASE2 | RNASE2CP | RNASE3 | RNASE4 | RNASE6 | RNASE7 | RNASE8 | RNASE9 | RNASEH1 | RNASEH1-DT | RNASEH2A | RNASEH2B | RNASEH2B-AS1 | RNASEH2C | RNASEH2CP1 | RNASEK | RNASEL | RNASET2 | RND1 | RND2 | RND3 | RNF10 | RNF103 | RNF103-CHMP3 | RNF11 | RNF111 | RNF112 | RNF113A | RNF113B | RNF114 | RNF115 | RNF121 | RNF122 | RNF123 | RNF125 | RNF126 | RNF126P1 | RNF128 | RNF13 | RNF130 | RNF133 | RNF135 | RNF138 | RNF138P1 | RNF139 | RNF139-DT | RNF14 | RNF141 | RNF144A | RNF144B | RNF145 | RNF146 | RNF148 | RNF149 | RNF150 | RNF151 | RNF152 | RNF157 | RNF157-AS1 | RNF165 | RNF166 | RNF167 | RNF168 | RNF169 | RNF17 | RNF170 | RNF175 | RNF180 | RNF181 | RNF182 | RNF183 | RNF185 | RNF186 | RNF187 | RNF19A | RNF19B | RNF2 | RNF20 | RNF207 | RNF208 | RNF212 | RNF212B | RNF213 | RNF213-AS1 | RNF214 | RNF215 | RNF216 | RNF216-IT1 | RNF216P1 | RNF217 | RNF217-AS1 | RNF220 | RNF222 | RNF224 | RNF225 | RNF227 | RNF24
