GSTM1: Potential Drug Target Or Biomarker (G2944)

Target Name: GSTM1

NCBI ID: G2944

GSTM1

GSTM1: Potential Drug Target Or Biomarker

GSTM1 (Glutathione S-transferase mu 1, transcript variant 1) is a gene that encodes a protein known as GSTM1. GSTM1 is a member of the GST family of transmembrane proteins, which are involved in the transfer of genetic information from DNA to RNA and vice versa. GSTM1 is primarily expressed in the liver, where it plays a role in the detoxification and metabolism of xenobiotics, such as drugs and other harmful substances.

GSTM1 has been shown to be involved in many different cellular processes in the body, including the detoxification of xenobiotics, inflammation, and cell signaling. GSTM1 has also been linked to a number of diseases, including liver disease and certain types of cancer.

Due to its involvement in a number of important cellular processes, GSTM1 has potential as a drug target or biomarker. For example, GSTM1 has been shown to be involved in the metabolism of drugs, which could make it an attractive target for drugs that are designed to modulate GSTM1 activity. Additionally, GSTM1 has been shown to be involved in inflammation, which could make it an attractive target for drugs that are designed to dampen inflammation.

GSTM1 has also been shown to be involved in the detoxification of xenobiotics, which could make it an attractive target for drugs that are designed to modulate GSTM1 activity in the context of xenobiotics.

In addition to its potential as a drug target or biomarker, GSTM1 has also been shown to be involved in a number of other cellular processes that are important for human health. For example, GSTM1 has been shown to play a role in the development and progression of certain types of cancer, as well as in the regulation of cell signaling and metabolism.

Overall, GSTM1 is a protein that has significant potential as a drug target or biomarker. Further research is needed to fully understand the role of GSTM1 in human health and to develop effective treatments based on its activity.

Protein Name: Glutathione S-transferase Mu 1

Functions: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276)

The "GSTM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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