Target Name: RNASE10
NCBI ID: G338879
Review Report on RNASE10 Target / Biomarker Content of Review Report on RNASE10 Target / Biomarker
RNASE10
Other Name(s): ribonuclease A family member 10 (inactive) | Ribonuclease 10 | ribonuclease A H1 | Ribonuclease-like protein 10 | RAH1 | RNS10_HUMAN | RNASE9 | inactive ribonuclease-like protein 10 | Ribonuclease A family member 10 (inactive), transcript variant 2 | ribonuclease, RNase A family, 10 (non-active) | Inactive ribonuclease-like protein 10 | RNASE10 variant 2

Unlocking the Potential of RNASE10 as a Drug Target: A Potential Biomarker for Antibiotic Resistance

The discovery of new biomarkers and drug targets is at the forefront of modern medicine, and RNA-based technologies have revolutionized the field of genetics. One such promising RNA molecule is RNASE10, a member of the Ribonuclease A family 10 (RNBEC) that is expressed in various cell types. In this article, we will explore the potential of RNASE10 as a drug target and its potential as a biomarker for antibiotic resistance.

The Ribonuclease A Family 10 (RNBEC)

Ribonuclease A family 10 (RNBEC) is a subfamily of RNAases that are involved in the breakdown of RNA, specifically microRNAs. These enzymes are classified based on their three-dimensional structure and their catalytic mechanism. RNBECs are classified into three subfamilies: RNBEC 1, RNBEC 2, and RNBEC 3. RNASE10 is a member of the RNBEC 2 subfamily and is characterized by its unique three-dimensional structure that consists of a catalytic core and a monomeric subunit.

Function and Expression

RNA-based technologies have extensively been used to study the function and expression of RNAases, including RNBECs. Studies have shown that RNBECs are involved in various cellular processes, including cell growth, apoptosis, and transcriptosome formation. They are also involved in the regulation of gene expression and play a crucial role in the control of post-transcriptional modifications, such as splicing and translation.

RNAase activity

RNAase activity is a key function of RNBECs, and RNASE10 is no exception. The catalytic core of RNase10 contains a specific active site that allows it to cleave double-stranded RNA with high accuracy. Studies have shown that RNase10 can cleave various types of RNA, including microRNAs, pre-mRNA, and post-mRNA. In addition, RNase10 can also participate in the regulation of RNA stability and can interact with various cellular factors, such as the RNA-protein complex.

Drug targeting

The potential of RNase10 as a drug target is high due to its unique function and its involvement in various cellular processes. Drugs that target RNase10 have the potential to inhibit its activity and disrupt its role in cellular processes. This could lead to therapeutic benefits, such as the treatment of various diseases associated with overactive RNAases.

Biomarker potential

The potential of RNase10 as a biomarker for antibiotic resistance comes from its involvement in the regulation of gene expression and its role in the control of post-transcriptional modifications. Antibiotics are known to target bacterial RNAases, which are also involved in the regulation of gene expression. By inhibiting the activity of RNase10, antibiotics may be able to enhance their effectiveness and reduce the risk of antibiotic resistance.

Conclusion

In conclusion, RNASE10 is a promising RNA molecule that has the potential to serve as a drug target for its unique function and its involvement in various cellular processes. The potential of RNase10 as a biomarker for antibiotic resistance is also significant due to its involvement in the regulation of gene expression and post-transcriptional modifications. Further research is needed to fully understand the potential of RNase10 as a drug target and its potential as a biomarker for antibiotic resistance.

Protein Name: Ribonuclease A Family Member 10 (inactive)

Functions: Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity)

The "RNASE10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RNASE10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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