Target Name: PLEC
NCBI ID: G5339
Review Report on PLEC Target / Biomarker Content of Review Report on PLEC Target / Biomarker
PLEC
Other Name(s): EBSMD | LGMDR17 | PLEC variant 1 | Plectin | PLTN | PLEC variant 6 | Plectin (isoform 1c) | LGMD2Q | Plectin (isoform 1g) | plectin 1, intermediate filament binding protein 500kDa | EBS5D | Hemidesmosomal protein 1 | Plectin 1, intermediate filament binding protein 500kDa | Plectin (isoform 1) | Plectin, transcript variant 6 | Plectin 1 | Plectin (isoform 1a) | Plectin, transcript variant 11 | Plectin (isoform 1f) | PLEC variant 2 | PLEC_HUMAN | EBS5A | PLEC1b | Plectin, transcript variant 1 | EBS5B | EBSPA | Plectin, transcript variant 10 | Plectin, transcript variant 2 | HD1 | EBSOG | PLEC variant 11 | hemidesmosomal protein 1 | EBS5C | PLEC1 | Plectin-1 | EBS1 | EBSO | EBSND | PLEC variant 10 | plectin | PCN

PLEC: A Potential Drug Target and Biomarker

Pleiotropic Effects Compound (PLEC) is a protein that is expressed in various tissues and cells throughout the body. It has been shown to have a wide range of effects on various cellular processes, including cell signaling, inflammation, and stress resistance. As a result, PLEC has potential as a drug target and biomarker.

The protein PLEC is composed of 128 amino acid residues and has a calculated molecular mass of 13.9 kDa. It is expressed in various tissues, including the brain, heart, liver, and kidneys. PLEC is involved in a number of cellular processes, including cell signaling, cell adhesion, and stress response.

One of the most significant functions of PLEC is its role in cell signaling. PLEC has been shown to play a role in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in the development and maintenance of tissues, and is a key factor in the development of cancer.

In addition to its role in cell signaling, PLEC is also involved in the regulation of cell adhesion. PLEC has been shown to play a role in the formation of tight junctions, which are a type of cell adhesion structure that helps to maintain the integrity of tissues.

PLEC is also involved in the regulation of stress response. PLEC has been shown to play a role in the stress response pathway, which is involved in the regulation of cellular stress responses. This pathway is important for the survival of cells in a variety of environments, including those that are subjected to stress, such as those that are exposed to toxins or radiation.

In addition to its role in cell signaling, PLEC is also involved in the regulation of inflammation. PLEC has been shown to play a role in the regulation of inflammation, including the regulation of the immune response. This is important for maintaining the health and function of tissues, and is a key factor in the development of diseases such as cancer.

As a potential drug target, PLEC is an attractive target for drug development due to its diverse range of functions. PLEC has been shown to play a role in a wide range of cellular processes, including cell signaling, cell adhesion, and stress response. This makes it an attractive target for drugs that are designed to modulate these processes, including those that are used to treat a variety of diseases, such as cancer, heart disease, and neurological disorders.

In addition to its potential as a drug target, PLEC also has potential as a biomarker. PLEC has been shown to have a wide range of effects on various cellular processes, including cell signaling, cell adhesion, and stress response. This makes it an attractive candidate for use as a biomarker for a variety of diseases. For example, PLEC has been shown to be involved in the regulation of the immune response, which makes it an attractive candidate for use as a biomarker for diseases such as cancer.

In conclusion, PLEC is a protein that is involved in a wide range of cellular processes, including cell signaling, cell adhesion, and stress response. As a result, PLEC has potential as a drug target and biomarker. Further research is needed to fully understand the functions of PLEC and its potential as a drug target and biomarker.

Protein Name: Plectin

Functions: Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity

The "PLEC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLEC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLEK | PLEK2 | PLEKHA1 | PLEKHA2 | PLEKHA3 | PLEKHA4 | PLEKHA5 | PLEKHA6 | PLEKHA7 | PLEKHA8 | PLEKHA8P1 | PLEKHB1 | PLEKHB2 | PLEKHD1 | PLEKHF1 | PLEKHF2 | PLEKHG1 | PLEKHG2 | PLEKHG3 | PLEKHG4 | PLEKHG4B | PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH