GSTK1 as A Drug Target Or Biomarker for Diseases (G373156)

Target Name: GSTK1

NCBI ID: G373156

GSTK1

GSTK1 as A Drug Target Or Biomarker for Diseases

GSTK1 (GST13-13) is a protein that is expressed in various tissues and cells in the body. It is a key regulator of the gamma-glutamyl transferase (GGT) enzyme, which is involved in the metabolism of several compounds, including drugs. As a result, GSTK1 has been identified as a potential drug target or biomarker for several diseases.

The GGT enzyme is a transmembrane protein that is expressed in the liver, lung, and other tissues. It is involved in the metabolism of a wide variety of drugs, including many statins, which are used to treat high cholesterol. GSTK1 is a critical regulator of GGT activity, and it has been shown to play a role in the metabolism of many drugs.

One of the ways that GSTK1 is involved in drug metabolism is by modulating the activity of GGT. GSTK1 has been shown to interact with GGT and to regulate its activity. This interaction between GSTK1 and GGT has important implications for drug development, as it allows researchers to better understand how drugs are metabolized and how they can be optimized for use.

In addition to its role in drug metabolism, GSTK1 is also involved in the regulation of cellular processes that are important for overall health and disease. For example, GSTK1 has been shown to play a role in the regulation of cell signaling pathways, which are involved in the development and progression of many diseases, including cancer.

GSTK1 has also been shown to be involved in the regulation of inflammation, which is a critical aspect of many diseases, including cancer. GSTK1 has been shown to play a role in the regulation of the immune response, as well as in the regulation of inflammation.

GSTK1 has also been shown to be involved in the regulation of cellular aging, which is a critical aspect of the development of many diseases, including cancer. GSTK1 has been shown to play a role in the regulation of the DNA damage response, which is involved in the regulation of cellular aging.

In conclusion, GSTK1 is a protein that is involved in a wide range of cellular processes that are important for overall health and disease. As a result, GSTK1 has been identified as a potential drug target or biomarker for several diseases, including cancer, heart disease, and neurological disorders. Further research is needed to fully understand the role of GSTK1 in these diseases and to develop effective treatments.

Protein Name: Glutathione S-transferase Kappa 1

Functions: Glutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed:14709161, PubMed:14742434). Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB) (PubMed:14709161)

The "GSTK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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