Target Name: GSN
NCBI ID: G2934
Review Report on GSN Target / Biomarker Content of Review Report on GSN Target / Biomarker
GSN
Other Name(s): Gelsolin, transcript variant X11 | actin-depolymerizing factor | GSN variant 1 | Gelsolin, transcript variant 3 | epididymis secretory sperm binding protein | GSN variant 3 | Gelsolin (isoform b) | gelsolin | Gelsolin | GSN variant X11 | Gelsolin (isoform a) | GELS_HUMAN | GSN variant 4 | Gelsolin, transcript variant 1 | Gelsolin (isoform X4) | Actin-depolymerizing factor | Brevin | ADF | AGEL | Gelsolin (isoform f) | brevin | Gelsolin, transcript variant 4

GSN: A Protein Regulator of Cell Division, Cell Migration and Tissue Formation

GSN, or Gelsolin transcript variant X11, is a protein that is expressed in various tissues and cells throughout the body. It is a key regulator of the actin cytoskeleton, which is the structure that gives cells their shape and stability. GSN plays a crucial role in the regulation of cell division, cell migration, and the formation of tissues.

GSN is composed of 251 amino acid residues and has a molecular weight of 31 kDa. It is a monomeric protein that consists of a single polypeptide chain. GSN is expressed in a variety of tissues and cells throughout the body, including muscle cells, nerve cells , heart cells, and blood cells.

GSN is involved in the regulation of cell division and cell cycle progression. It plays a role in the metaphase of cell division, where the chromosomes are replicated and the replicated chromosomes move to the opposite extreme of the cell. During metaphase, GSN helps to ensure that the chromosomes are properly organized and that the cell divides correctly.

In addition to its role in cell division, GSN is also involved in the regulation of cell migration. It helps to maintain the integrity of the cytoskeleton, which is necessary for the movement of cells. GSN also helps to regulate the formation of tissues by ensuring that the cytoskeleton is properly organized and that the cell division is correctly regulated.

GSN has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of the immune response and the regulation of inflammation.

GSN is also a potential drug target. Its role in the regulation of cell division, cell cycle progression, and cell migration makes it an attractive target for drug development. Additionally, its role in the regulation of inflammation makes it a potential target for the treatment of inflammatory diseases.

GSN has also been shown to play a role in the regulation of the blood cell formation. It is expressed in the bone marrow and plays a role in the production of red blood cells, which are responsible for carrying oxygen from the lungs to the rest of the body.

In conclusion, GSN is a protein that is involved in the regulation of cell division, cell cycle progression, and cell migration. Its role in these processes makes it an attractive target for drug development. Additionally, its role in the regulation of inflammation makes it a potential target for the treatment of inflammatory diseases. Further research is needed to fully understand the role of GSN in these processes and to develop effective treatments.

Protein Name: Gelsolin

Functions: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed:19666512). Plays a role in ciliogenesis (PubMed:20393563)

The "GSN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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