Ulcerative Colitis
About the Disease
Inflammatory Bowel Disease 1, also known as inflammatory bowel disease 1, is related to inflammatory bowel disease 19 and inflammatory bowel disease 17, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Inflammatory Bowel Disease 1 is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Magnesium citrate and Prucalopride have been mentioned in the context of this disorder. Affiliated tissues include colon, bone marrow and bone, and related phenotypes are growth delay and abdominal pain
Common Targets
G25816 | G347732 | G3557 | P12956 | G7100 | G4982 | G4868 | G2859 | G10612 | G202 | G105375194 | G105379570 | G9577 | G10892 | G3309 | G5771 | G120892 | G137196 | G138882 | G4513 | G4593 | G23533 | G2936 | G105375195 | G113 | G3572 | G6336 | G138046 | P5760 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | G100133941 | G1445 | G2150 | G781 | G253461 | Corticotropin-Releasing Factor (CRF) Receptor (nonspecified subtype) | G1390 | G1991 | G7185 | G284825 | G919 | P8262 | G4615 | G23569 | G105379648 | Tyrosine-Protein Kinases Src (nonspecified subtype) | G63971 | P6176 | cAMP Phosphodiesterase (nonspecified subtype) | G64078 | G643749 | G944 | G1269 | G7450 | G100507530 | G11240 | G4627 | G5142 | G105379652 | G27178 | G8718 | G1019 | G6423 | G64446 | G150280 | G7975 | G51561 | G84286 | G283463 | G101927774 | G939 | G164592 | G8740 | G923 | Kainate Receptor (GluR) (nonspecified subtype) | G8993 | G3456 | G3559 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | G7157 | G105379658 | G1235 | G3710 | G4780 | G284889 | G26027 | G8470 | G1029 | G558 | G3106 | G105379663 | G7297 | G2280 | G57605 | G10800 | G11140 | G22904 | G4514 | G84876 | G55869 | G306 | G3123 | G57787 | G800 | G100507679 | G51174 | G80339 | G81796 | G90550 | G3459 | G56848 | G3417 | G4049 | G4772 | G57818 | G1807 | G1432 | G100137047 | G4314 | G55567 | G94025 | G3117 | G345611 | G64167 | G154810 | G7124 | G2217 | G541472 | G5578 | G5604 | G7172 | G220002 | G4650 | G7791 | G79930 | Lipoxygenase (nonspecified subtype) | G27072 | G9308 | G3902 | G3912 | G3932 | G7454 | G100526664 | G54973 | G11343 | G221395 | G864 | G10320 | G65250 | G23081 | G79054 | G10745 | G4939 | G27134 | G89792 | G5803 | G2065 | G8321 | G55628 | G3350 | G4217 | G201266 | G1723 | G2475 | G1268 | G3587 | G64087 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | P6463 | G23294 | G5468 | G11007 | G64321 | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | G391211 | G4851 | G50856 | G650 | G1611 | G171024 | G9817 | G4651 | G5535 | G109 | Mucin (nonspecified subtype) | G84952 | G2841 | G129684 | G140807 | G79705 | G51564 | G8784 | G54901 | G3383 | G3700 | G23411 | G10846 | G4535 | G81619 | P5761 | G3851 | G7038 | G84953 | G57094 | G7059 | G2357 | G8726 | G102659288 | G10544 | G5334 | G54870 | G5533 | G11262 | G3357 | G3575 | G6753 | G30009 | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | G5481 | G10970 | G6868 | G2788 | Alkaline Phosphatase (ALP) (nonspecified subtype) | G64127 | G534 | G929 | G56244 | G5742 | G7442 | G283234 | G55690 | G10425 | G64170 | P6320 | G7082 | G2193 | G7329 | G8517 | G1263 | G3594 | G79710 | G51393 | G8698 | G1326 | G400935 | G7277 | G89796 | G81490 | G3105 | G3577 | P5614 | G3758 | G105371082 | G942 | G3164 | G775 | G8743 | G11015 | G6609 | G174 | G1830 | G4762 | G23046 | G23263 | G80216 | G1015 | G958 | G3783 | G6550 | G80824 | G26737 | G9 | G9429 | P5561 | G387357 | G1803 | G55054 | G114609 | G6300 | alpha-Adrenoceptor (nonspecified subtype) | G8856 | G1013 | G146434 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | G4065 | G2494 | G6648 | G7332 | G10551 | P19243 | G6850 | G79587 | G9404 | G3336 | G3605 | G6424 | P5864 | P6884 | G2908 | G3248 | G1244 | P24881 | G403150 | G54756 | G999 | G391475 | G2159 | G7412 | G23187 | G54535 | G962 | G2876 | G158747 | G79258 | G53345 | G3600 | G144811 | G4689 | G553103 | G105369438 | G952 | P16176 | G7074 | G231 | G83696 | G89797 | G10210 | G2952 | G5770 | Histone acetyltransferase (HAT) (nonspecified subtype) | G166379 | P40594 | G4092 | G26273 | G2214 | G84439 | G1591 | G81628 | G54986 | G11273 | G3630 | G79648 | G3460 | G8745 | G54790 | G9158 | G10554 | G3122 | G7498 | G5290 | G29121 | G1789 | G286046 | G5743 | G6016 | G2147 | G51135 | G80736 | G56165 | G3595 | P5833 | G1903 | G7097 | G4318 | G54538 | G3676 | G6566 | G406907 | G7535 | G80835 | G51460 | G8788 | G2867 | G63027 | G9175 | G7837 | G246778 | G25981 | G2646 | G92949 | G729920 | G7517 | G2289 | G84617 | G23548 | G85480 | G105371388 | G143662 | G150577 | G321 | CDK6/Cyclin D1 | G6610 | G4233 | G53347 | G9971 | G6356 | G80005 | G163486 | G5243 | G114625 | G6754 | G79058 | G105374211 | G3310 | G11184 | G60468 | G140 | Sodium channel (nonspecified subtype) | G2355 | G84619 | G274 | G5734 | G337867 | G6660 | G54908 | G3096 | P5662 | G391723 | G7421 | G5580 | G931 | G59307 | G6279 | G4537 | G2877 | G5859 | G3554 | G4046 | G22948 | G79026 | G9071 | G5540 | G3859 | G1984 | Interferon alpha/beta Receptor (nonspecified subtype) | G51198 | G7141 | G2064 | G221895 | G7466 | G2538 | G84162 | G597 | G2868 | G646498 | G1493 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | G6567 | G4087 | G23131 | G79722 | G4291 | G8876 | G3800 | G81542 | Toll-Like Receptor (nonspecified subtype) | G2322 | G260425 | G10018 | G54542 | G11026 | G6775 | G2166 | G53831 | G151790 | G2194 | G4795 | G9759 | G112744 | G3558 | Caspase (nonspecified subtype) | G2255 | G105369736 | G5591 | G56956 | G57580 | G4313 | G23344 | G79954 | G9734 | G636 | G1577 | G4846 | G84441 | G6404 | G50937 | G3552 | G3586 | G152273 | G6532 | G1956 | G8288 | G54546 | G8807 | G9262 | G5888 | G1266 | G9891 | P11025 | G5036 | G285626 | G6048 | P19878 | G5536 | G10803 | Heat shock protein 70 (nonspecified subtype) | G23235 | G941 | G4583 | G10636 | G57162 | G8189 | G2153 | G356 | G158471 | G6441 | G406968 | G25845 | G57733 | G343406 | G5579 | G3802 | G196 | G4538 | G9075 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | G3458 | P6321 | G1605 | G54106 | G64682 | G5605 | G6583 | G406909 | G23416 | G55760 | G6425 | P6348 | G7166 | G7422 | G760 | G338440 | Tryptase (nonspecified subtype) | G64332 | Janus Kinase (nonspecified subtype) | G23062 | G4946 | G23522 | G56603 | G6037 | G2358 | G10293 | G3269 | G3579 | G4843 | G26191 | G392255 | G53637 | G57222 | G3592 | G8989 | G144195 | G10320 | G2548 | G9267 | G7428 | G92211 | G135114 | Histone deacetylase (nonspecified subtype) | G51752 | G8877 | G159296 | G4255 | G84067 | G101927242 | G3553 | G387755 | G221416 | G8808 | G10462 | G2212 | G50940 | G25940 | G28231 | P46614 | G406938 | G6869 | G83716 | G57684 | G1234 | G3627 | G4539 | G7293 | G2752 | G8927 | G2950 | G58492 | G3803 | G83888 | G5532 | G6755 | G5008 | G5328 | G1044 | G2944 | G3082 | G57016 | G324 | G114770 | G120400 | G5493 | G10295 | G6364 | G10599 | G56913 | G116349 | G114771 | G3569 | G26279 | G54827 | G5534 | G9123 | G10463 | G145264 | G168975 | G4088 | G55765 | G5588 | G213 | G220388 | G5141 | G9340 | G105376548 | G1364 | G79048 | G55076 | G3565 | G55974 | G105376550 | G118426 | G4282 | G84750 | G5317 | G9966 | Phospholipase A2, Secretory (sPLA2) (nonspecified subtype) | G728 | G4678 | G56288 | G59067 | G343641 | G6856 | G23418 | G5432 | G9223 | G2984 | G105372267 | G332 | G340061 | P16740 | P34548 | G54583 | G9180 | G10807 | G3172 | G2160 | G2625 | G64342 | G1755 | G5027 | G1240 | G3818 | G79068 | G6584 | G4363 | G2524 | G348 | G3718 | G100996324 | G92736 | G3570 | Sphingolipid delta(4)-desaturase (nonspecified subtype) | G3717 | G6621 | G27163 | G3716 | G51185 | G94103 | G26973 | G10333 | G943 | G11103 | G117194 | G1499 | G1672 | G1814 | G2149 | G240 | G10568 | G320 | G79611 | G8435 | G100529261 | G23203 | G3576 | G472 | G10241 | G3107 | G11315 | G114548 | G3596 | G390037 | G4126 | G2058 | G285834 | G10524 | G3439 | G64114 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | G8174 | G545 | G8844 | G3683 | G646982 | G7132 | G119587 | G4129 | G23245 | G170960 | G406973 | G414236 | G84552 | G125963 | G130132 | G79671 | G8737 | G3119 | G6369 | G1901 | G25953 | G10083 | G9290 | Serine/Threonine-Protein Kinases SIK (nonspecified subtype) | G5294 | G55374 | G51284 | G4292 | G4436 | G80762 | G100507436 | G100996485 | G89845 | G123099 | G1401 | G6664 | G1840 | G64699 | P6058 | G8560 | G5788 | G146198 | G4048 | G105376823 | G10758 | G1141 | G344 | G3606 | G102723364 | G9936 | G3667 | G440934 | G5347 | G53905 | G5581 | G149233 | G2215 | G147949 | G4485 | G8477 | G134864 | P5759 | G3737 | G745 | G7036 | G200942 | G4312 | G115727 | G6331 | G2353 | G23387 | G8028 | G2904 | G5133 | G8639 | G58985 | G124626 | G100302145 | G3604 | G6891 | G5724 | P11049 | G6774 | G4588 | G5549 | Melanocortin receptor (nonspecified subtype) | G2525 | G2581 | G100996583 | G105370158 | G22973 | G102723567 | G4353 | G339479 | P16091 | G57038 | G1215 | P5681 | G5139 | G102465500 | G11085 | G5777 | Superoxide dismutase (SOD) (nonspecified subtype) | G128611 | G3560 | G6647 | G105370177 | G63892 | Peptidyl arginine deiminase (PAD) (nonspecified subtype) | G4790 | G8506 | Glutathione peroxidase (nonspecified subtype) | P16165 | P29647 | G391059 | G7096 | G51611 | G54453 | G8985 | G57178 | G313 | G116444 | Defensin (nonspecified subtype) | G57491 | G402055 | G5144 | G55024 | G105370273 | G84128 | G10013 | G10666 | G1138 | G7494 | G6097 | G7005 | G5478 | G9863 | G84276 | G8767 | G3593 | G4157 | G7184 | G22900 | G51617 | G5320 | G2768 | G595 | G7991 | G847 | G3055 | G60 | P6747 | G7040 | G4703 | G51311 | P16683 | G165545 | G414764 | G441108 | G8975 | P5859 | G7375 | G253430 | G140733 | G7099 | G79473 | G55094 | G3091 | G119682 | CDK4/Cyclin D1 | G917 | G6524 | G152485 | G100996758 | G1012 | G22933 | G50515 | G2668 | G150223 | G7098 | G151306 | G4089 | G101927745 | G64579 | Interleukin 17 (nonspecified subtype) | G4040 | G90865 | G64116 | G643 | G150962 | G3812 | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype)
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Ulcerative Colitis, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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